2023
A Versatile Synaptotagmin-1 Nanobody Provides Perturbation-Free Live Synaptic Imaging And Low Linkage-Error in Super-Resolution Microscopy.
Queiroz Zetune Villa Real K, Mougios N, Rehm R, Sograte-Idrissi S, Albert L, Rahimi AM, Maidorn M, Hentze J, Martínez-Carranza M, Hosseini H, Saal KA, Oleksiievets N, Prigge M, Tsukanov R, Stenmark P, Fornasiero EF, Opazo F.
Small Methods. 2023 Jul 8:e2300218. doi: 10.1002/smtd.202300218. Online ahead of print.
Heat denaturation enables multicolor X10-STED microscopy.
Saal KA, Shaib AH, Mougios N, Crzan D, Opazo F, Rizzoli SO.
Sci Rep. 2023 Apr 1;13(1):5366. doi: 10.1038/s41598-023-32524-5.
Visualizing proteins by expansion microscopy.
Shaib AH, Chouaib AA, Chowdhury R, Mihaylov D, Zhang C, Imani V, Georgiev SV, Mougios N, Monga M, Reshetniak S, Mimoso T, Chen H, Fatehbasharzad P, Crzan D, Saal KA, Alawar N, Eilts J, Kang J, Alvarez L, Trenkwalder C, Mollenhauer B, Outeiro TF, Köster S, Preobraschenski J, Becherer U, Moser T, Boyden ES, Aricescu AR, Sauer M, Opazo F, Rizzoli SO.
Preprint: BioRxiv. 30 March 2023. doi: 10.1101/2022.08.03.502284.
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2021
Rho-kinase inhibition by fasudil modulates pre-synaptic vesicle dynamics.
Saal KA, Warth Pérez Arias C, Roser AE, Christoph Koch J, Bähr M, Rizzoli SO, Lingor P.
J Neurochem. 2021 May;157(4):1052-1068. doi: 10.1111/jnc.15274. Epub 2021 Jan 6.
2019
Boron-Containing Probes for Non-Optical High-Resolution Imaging of Biological Samples.
Kabatas S, Agüi-Gonzales P, Saal KA, Jähne S, Opazo F, Rizzoli SO, Phan TNN.
Angew Chem Int Ed Engl. 2019 Mar 11;58(11):3438-3443. doi: 10.1002/anie.201812032. Epub 2019 Feb 6.
View at PubMed
Boron-Containing Probes for Non-Optical High-Resolution Imaging of Biological Samples.
Kabatas S, Agüi-Gonzales P, Saal KA, Jähne S, Opazo F, Rizzoli SO, Phan TNN.
Angew Chem 2019 Mar 11;131(11):3476-3481. doi:10.1002/anie.201812032. Epub 2019 Jan 7.
2018
ROCK inhibition in models of neurodegeneration and its potential for clinical translation.
Koch JC, Tatenhorst L, Roser AE, Saal KA, Tönges L, Lingor P.
Pharmacol Ther. 2018 Sep;189:1-21. doi: 10.1016/j.pharmthera.2018.03.008. Epub 2018 Apr 3.
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Combined Use of Unnatural Amino Acids Enables Dual-Color Super-Resolution Imaging of Proteins via Click Chemistry.
Saal KA, Richter F, Rehling P, Rizzoli SO.
ACS Nano. 2018 Dec 26;12(12):12247-12254. doi: 10.1021/acsnano.8b06047. Epub 2018 Dec 13.
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2016
Altered expression of growth associated protein-43 and rho kinase in human patients with Parkinson´s disease.
Saal KA, Galter D, Roeber S, Bähr M, Tönges L, Lingor P.
Brain Pathol. 2016 Jan 8. doi: 10.1111/bpa.12346.
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2015
AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson’s disease in vitro and in vivo.
Saal KA, Koch JC, Tatenhorst L, Szegő EM, Ribas VT, Michel U, Bähr M, Tönges L, Lingor P.
Neurobiol Dis. 2015 Jan;73:150-62. doi: 10.1016/j.nbd.2014.09.013. Epub 2014 Oct 2.
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2014
The rho kinase inhibitor Y-27632 improves motor performance in male SOD1(G93A) mice.
Günther R, Saal KA, Suhr M, Scheer D, Koch JC, Bähr M, Lingor P, Tönges L.
Front Neurosci. 2014 Oct 7;8:304. doi: 10.3389/fnins.2014.00304. eCollection 2014.
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Alpha-synuclein mutations impair axonal regeneration in models of Parkinson’s disease.
Tönges L, Szegö EM, Hause P, Saal KA, Tatenhorst L, Koch JC, D Hedouville Z, Dambeck V, Kügler S, Dohm CP, Bähr M, Lingor P.
Front Aging Neurosci. 2014 Sep 10;6:239. doi: 10.3389/fnagi.2014.00239. eCollection 2014.
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Rho kinase inhibition by fasudil in the striatal 6-hydroxydopamine lesion mouse model of Parkinson disease.
Tatenhorst L, Tönges L, Saal KA, Koch JC, Szegő ÉM, Bähr M, Lingor P.
J Neuropathol Exp Neurol. 2014 Aug;73(8):770-9. doi: 10.1097/NEN.0000000000000095.
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Rho kinase inhibition modulates microglia activation and improves survival in a model of amyotrophic lateral sclerosis.
Tönges L, Günther R, Suhr M, Jansen J, Balck A, Saal KA, Barski E, Nientied T, Götz AA, Koch JC, Mueller BK, Weishaupt JH, Sereda MW, Hanisch UK, Bähr M, Lingor P.
Glia. 2014 Feb;62(2):217-32. doi: 10.1002/glia.22601. Epub 2013 Dec 6.
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2012
Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson’s disease.
Tönges L, Frank T, Tatenhorst L, Saal KA, Koch JC, Szego ÉM, Bähr M, Weishaupt JH, Lingor P.
Brain. 2012 Nov;135(Pt 11):3355-70. doi: 10.1093/brain/aws254. Epub 2012 Oct 19.
View at Pubmed